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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA2
All Species:
19.7
Human Site:
S2289
Identified Species:
36.11
UniProt:
Q9BZC7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZC7
NP_001597
2435
269873
S2289
I
T
V
R
T
K
S
S
Q
S
V
K
D
V
V
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
S2202
A
V
V
L
T
S
H
S
M
E
E
C
E
A
L
Rhesus Macaque
Macaca mulatta
XP_001117819
2476
273629
S2316
I
T
V
R
T
K
S
S
Q
S
V
K
D
V
V
Dog
Lupus familis
XP_537788
2395
264756
S2241
I
T
V
R
T
K
S
S
Q
N
V
K
D
V
V
Cat
Felis silvestris
Mouse
Mus musculus
P41234
2434
270490
S2290
I
T
V
R
T
K
S
S
Q
N
V
K
D
V
V
Rat
Rattus norvegicus
Q9ESR9
2434
270910
S2290
I
T
V
R
T
K
S
S
Q
N
V
K
D
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
C2129
M
V
N
G
R
F
R
C
L
G
S
V
Q
H
L
Chicken
Gallus gallus
XP_422330
2276
256293
G2139
R
L
A
I
M
V
K
G
T
F
K
C
L
G
T
Frog
Xenopus laevis
NP_001089022
2363
267334
V2223
C
T
R
L
A
I
M
V
K
G
K
F
K
C
L
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
C2131
M
V
N
G
R
F
R
C
L
G
S
V
Q
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
E1567
S
H
S
M
D
E
C
E
A
L
C
S
R
I
A
Sea Urchin
Strong. purpuratus
XP_798273
1913
213253
E1776
C
L
G
V
P
E
G
E
C
F
G
L
L
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
E1744
P
D
T
A
S
A
S
E
I
S
L
S
P
E
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.1
96
82.2
N.A.
91
92.9
N.A.
39.1
35.7
36.5
37.7
N.A.
N.A.
N.A.
23.7
41.7
Protein Similarity:
100
52
96.6
86.1
N.A.
93.2
94.9
N.A.
55.7
53.5
54.7
54.5
N.A.
N.A.
N.A.
39
54.4
P-Site Identity:
100
20
100
93.3
N.A.
93.3
93.3
N.A.
0
0
6.6
0
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
13.3
0
20
13.3
N.A.
N.A.
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
8
0
0
8
0
0
0
0
8
8
% A
% Cys:
16
0
0
0
0
0
8
16
8
0
8
16
0
8
0
% C
% Asp:
0
8
0
0
8
0
0
0
0
0
0
0
39
0
0
% D
% Glu:
0
0
0
0
0
16
0
24
0
8
8
0
8
8
0
% E
% Phe:
0
0
0
0
0
16
0
0
0
16
0
8
0
0
0
% F
% Gly:
0
0
8
16
0
0
8
8
0
24
8
0
0
16
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
16
0
% H
% Ile:
39
0
0
8
0
8
0
0
8
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
39
8
0
8
0
16
39
8
0
0
% K
% Leu:
0
16
0
16
0
0
0
0
16
8
8
8
16
0
31
% L
% Met:
16
0
0
8
8
0
8
0
8
0
0
0
0
0
8
% M
% Asn:
0
0
16
0
0
0
0
0
0
24
0
0
0
0
0
% N
% Pro:
8
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
39
0
0
0
16
0
0
% Q
% Arg:
8
0
8
39
16
0
16
0
0
0
0
0
8
0
0
% R
% Ser:
8
0
8
0
8
8
47
47
0
24
16
16
0
0
0
% S
% Thr:
0
47
8
0
47
0
0
0
8
0
0
0
0
0
8
% T
% Val:
0
24
47
8
0
8
0
8
0
0
39
16
0
39
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _